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CellMed 2023; 13(9): 3.1-3.4

Published online July 31, 2023

https://doi.org/10.5667/CellMed.spc.035

© Cellmed Orthocellular Medicine and Pharmaceutical Association

세포교정영양요법(OCNT)을 이용한 무좀 개선 사례 연구

박정미 약사

경기도 부천시 성주로 267 메디팜비타민약국

A Case Study on the Improvement of Athlete's Foot Using Ortho-Cellular Nutrition Therapy (OCNT)

Pharmacist, Jung-mi Park

Medipharm Vitamin Pharmacy, 267 Seongju-ro, Bucheon-si, Gyeonggi-do, Republic of Korea

Correspondence to : *Jung-mi Park
E-mail: lemon220@hanmail.net

Received: July 27, 2023; Accepted: July 28, 2023

Objective: A case report on the improvement of athlete's foot using Ortho-Cellular Nutrition Therapy (OCNT).
Methods: A Korean male in his 50s is suffering from athlete's foot for 10 years.
Results: Keratinization of the soles and deformity of the toenails were alleviated after undergoing OCNT.
Conclusion: Application of OCNT to patients with athlete's foot can help protect the skin barrier and improve symptoms.

Keywords Ortho-Cellular Nutrition Therapy (OCNT), athlete's foot

Athletés foot (tinea pedis) is a chronic fungal infection of the feet, and it is often observed in immunosuppressed patients or those with diabetes. In the United States, it is estimated to be the second most common skin condition following acne, which indicates that it affects a maximum of 15% of the population.

Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum are identified as the causative organisms of athletés foot.1 Athletés foot can spread not only to the feet, but also to the rest of the body, and in worst cases, to others.2 Topical Terbinafine has a 70% rate of full recovery, while Tolnaftate and Miconazole take about 2-4 weeks for complete recovery.3

However, the patient, in this case, explained that other medications did not work well, and the athletés foot continued to become more severe. After using Sulfoplex Cream Mild, the symptoms of the athletés foot were significantly improved, and this case report is provided with the consent of the patient.

1. Target

It targeted one patient with athletés foot.

1) Name: Park, O O (M/54 years old)

2) Diagnosis: Athlete’s foot

3) Date of Onset: January 2012

4) Treatment Period: For 33 days in 2023

5) Chief Complaint: Total infection of both feet and toenails, severe keratinization of the soles of both feet

6) Past History: None

7) Social History: No history of smoking and alcohol

8) Family History: None

9) Current medication: None

2. Method

Sulfoplex Cream Mild (101, twice a day, appropriate amount applied to the affected area) Wash the feet, wipe completely, and let it absorb while massaging both feet and toenails.

The patient in this case developed athletés foot 10 years ago and made various attempts for treatment throughout the years. However, the nature of the patient's job makes it inevitable to develop athletés foot fungus, and since the condition had continued for a long time, both the heels and toenails of both feet were severely infected (Fig. 1). Advancement of severe keratinization was observed on the entire sole of the foot with cracks, but it was confirmed that keratinization and skin cracks were noticeably improved after undergoing OCNT (Fig. 1A). In addition, the patient had dark and thick toenails due to athletés foot bacteria that had penetrated the toenails at first, but the thickness of the toenails recovered to normal conditions after undergoing OCNT, and the color of the toenails also showed a clear difference compared to conditions prior to treatment (Fig. 1B).

Fig. 1. Comparison of the patient's condition before and after undergoing OCNT. (A) Changes in the patient's soles before and after undergoing OCNT. (B) Changes in the patient's toenails before and after undergoing OCNT.

ConsiderationThe patient is a male in his 50s, who runs a gas station and wears boots most of the time, which does not allow athletés foot bacteria to worsen to the point of covering both feet. All ten toenails were infected with athletés foot bacteria and turned white, even up to the point of deformation, and the soles of both feet were thick and cracked with dead skin cells due to keratinization. The patient tried using various medications for treatment, but no treatment effect was observed, and the athletés foot only got worse. The skin barrier of the patient was weakened by a long-lasting athletés foot, and it was determined that an existing external application could actually worsen the symptoms. Therefore, OCNT was performed because it seems that the protection of the skin barrier weakened by infection and the treatment of athletés foot bacteria must be performed simultaneously. MSM contained in Sulfoplex Cream Mild is effective in anti-inflammatory and immune functions, and4 cyanidin is capable of treating the fungus that causes athletés foot by reducing the length of the genital tract as well as the diameter of the growth of the fungus.5

In addition, centella asiatica and turmeric root treat inflammation caused by bacteria entering the body through cracked skin6,7, and they play the role of antibacterial action8,9 to prevent secondary infection.

Hyaluronic acid moisturizes dry feet by supplying moisture to the skin10, and sunflower seed oil11 and evening primrose oil12,13 are responsible for softening dead skin cells on the soles of the feet to normalize the skin barrier.

As this is a single case study, the findings may not be universally applicable to all patients with athletés feet. However, it is reported with the patient's consent as a case that has shown improvement in symptoms.

  1. Al Hasan, M., Fitzgerald, S. M., Saoudian, M. & Krishnaswamy, G. Dermatology for the practicing allergist: Tinea pedis and its complications. Clinical and Molecular Allergy 2, 1-11 (2004).
    Pubmed KoreaMed CrossRef
  2. Crawford, F. Athlete's foot. BMJ Clin Evid 2009 (2009).
  3. Markova, T. & Johnson, E. D. What is the most effective treatment for tinea pedis (athlete's foot)? (2002).
  4. Yu, W., Zhu, S.-G., Lu, S.-J., Cai, Z.-X. & Zang, L.-Q. Effect of dimethyl sulfone on anti-inflammatory and immune function in mice. Journal of Hainan Medical University 24, 899-901 (2018).
  5. Tao, S. et al. In vitro antifungal activity and mode of action of selected polyphenolic antioxidants on Botrytis cinerea. Archives of Phytopathology and Plant Protection 43, 1564-1578 (2010).
    CrossRef
  6. Goo, Y.-M. et al. Analysis of antibacterial, anti-inflammatory, and skin-whitening effect of Centella asiatica (L.) Urban. Journal of Plant Biotechnology 45, 117-124 (2018).
    CrossRef
  7. Bulbula, D. D. Comprehensive Review on Turmeric (Curcuma longa l.) as medicinal plant and its nutraceutical quality to human. Cancer therapy and Oncology International Journal 18, 1-3 (2021).
  8. Niamsa, N. & Sittiwet, C. Antimicrobial activity of Curcuma longa aqueous extract. Journal of Pharmacology and Toxicology 4, 173-177 (2009).
    CrossRef
  9. Mudaliana, S. Antimicrobial activity of Centella asiatica and Gigantochloa apus. Journal of Basic and Clinical Physiology and Pharmacology 32, 755-759 (2021).
    Pubmed CrossRef
  10. Jegasothy, S. M., Zabolotniaia, V. & Bielfeldt, S. Efficacy of a new topical nano-hyaluronic acid in humans. The Journal of clinical and aesthetic dermatology 7, 27 (2014).
  11. Danby, S. G. et al. Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care. Pediatric dermatology 30, 42-50 (2013).
    Pubmed CrossRef
  12. Kaźmierska, A. et al. Effect of Evening Primrose Oil Supplementation on Selected Parameters of Skin Condition in a Group of Patients Treated with Isotretinoin—A Randomized Double-Blind Trial. Nutrients 14, 2980 (2022).
    Pubmed KoreaMed CrossRef
  13. Timoszuk, M., Bielawska, K. & Skrzydlewska, E. Evening primrose (Oenothera biennis) biological activity dependent on chemical composition. Antioxidants 7, 108 (2018).
    Pubmed KoreaMed CrossRef

Article

Case Report

CellMed 2023; 13(9): 3.1-3.4

Published online July 31, 2023 https://doi.org/10.5667/CellMed.spc.035

Copyright © Cellmed Orthocellular Medicine and Pharmaceutical Association.

세포교정영양요법(OCNT)을 이용한 무좀 개선 사례 연구

박정미 약사

경기도 부천시 성주로 267 메디팜비타민약국

Received: July 27, 2023; Accepted: July 28, 2023

A Case Study on the Improvement of Athlete's Foot Using Ortho-Cellular Nutrition Therapy (OCNT)

Pharmacist, Jung-mi Park

Medipharm Vitamin Pharmacy, 267 Seongju-ro, Bucheon-si, Gyeonggi-do, Republic of Korea

Correspondence to:*Jung-mi Park
E-mail: lemon220@hanmail.net

Received: July 27, 2023; Accepted: July 28, 2023

Abstract

Objective: A case report on the improvement of athlete's foot using Ortho-Cellular Nutrition Therapy (OCNT).
Methods: A Korean male in his 50s is suffering from athlete's foot for 10 years.
Results: Keratinization of the soles and deformity of the toenails were alleviated after undergoing OCNT.
Conclusion: Application of OCNT to patients with athlete's foot can help protect the skin barrier and improve symptoms.

Keywords: Ortho-Cellular Nutrition Therapy (OCNT), athlete's foot

Introduction

Athletés foot (tinea pedis) is a chronic fungal infection of the feet, and it is often observed in immunosuppressed patients or those with diabetes. In the United States, it is estimated to be the second most common skin condition following acne, which indicates that it affects a maximum of 15% of the population.

Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum are identified as the causative organisms of athletés foot.1 Athletés foot can spread not only to the feet, but also to the rest of the body, and in worst cases, to others.2 Topical Terbinafine has a 70% rate of full recovery, while Tolnaftate and Miconazole take about 2-4 weeks for complete recovery.3

However, the patient, in this case, explained that other medications did not work well, and the athletés foot continued to become more severe. After using Sulfoplex Cream Mild, the symptoms of the athletés foot were significantly improved, and this case report is provided with the consent of the patient.

Cases

1. Target

It targeted one patient with athletés foot.

1) Name: Park, O O (M/54 years old)

2) Diagnosis: Athlete’s foot

3) Date of Onset: January 2012

4) Treatment Period: For 33 days in 2023

5) Chief Complaint: Total infection of both feet and toenails, severe keratinization of the soles of both feet

6) Past History: None

7) Social History: No history of smoking and alcohol

8) Family History: None

9) Current medication: None

2. Method

Sulfoplex Cream Mild (101, twice a day, appropriate amount applied to the affected area) Wash the feet, wipe completely, and let it absorb while massaging both feet and toenails.

Result

The patient in this case developed athletés foot 10 years ago and made various attempts for treatment throughout the years. However, the nature of the patient's job makes it inevitable to develop athletés foot fungus, and since the condition had continued for a long time, both the heels and toenails of both feet were severely infected (Fig. 1). Advancement of severe keratinization was observed on the entire sole of the foot with cracks, but it was confirmed that keratinization and skin cracks were noticeably improved after undergoing OCNT (Fig. 1A). In addition, the patient had dark and thick toenails due to athletés foot bacteria that had penetrated the toenails at first, but the thickness of the toenails recovered to normal conditions after undergoing OCNT, and the color of the toenails also showed a clear difference compared to conditions prior to treatment (Fig. 1B).

Figure 1. Comparison of the patient's condition before and after undergoing OCNT. (A) Changes in the patient's soles before and after undergoing OCNT. (B) Changes in the patient's toenails before and after undergoing OCNT.

Consideration

ConsiderationThe patient is a male in his 50s, who runs a gas station and wears boots most of the time, which does not allow athletés foot bacteria to worsen to the point of covering both feet. All ten toenails were infected with athletés foot bacteria and turned white, even up to the point of deformation, and the soles of both feet were thick and cracked with dead skin cells due to keratinization. The patient tried using various medications for treatment, but no treatment effect was observed, and the athletés foot only got worse. The skin barrier of the patient was weakened by a long-lasting athletés foot, and it was determined that an existing external application could actually worsen the symptoms. Therefore, OCNT was performed because it seems that the protection of the skin barrier weakened by infection and the treatment of athletés foot bacteria must be performed simultaneously. MSM contained in Sulfoplex Cream Mild is effective in anti-inflammatory and immune functions, and4 cyanidin is capable of treating the fungus that causes athletés foot by reducing the length of the genital tract as well as the diameter of the growth of the fungus.5

In addition, centella asiatica and turmeric root treat inflammation caused by bacteria entering the body through cracked skin6,7, and they play the role of antibacterial action8,9 to prevent secondary infection.

Hyaluronic acid moisturizes dry feet by supplying moisture to the skin10, and sunflower seed oil11 and evening primrose oil12,13 are responsible for softening dead skin cells on the soles of the feet to normalize the skin barrier.

As this is a single case study, the findings may not be universally applicable to all patients with athletés feet. However, it is reported with the patient's consent as a case that has shown improvement in symptoms.

Fig 1.

Figure 1.Comparison of the patient's condition before and after undergoing OCNT. (A) Changes in the patient's soles before and after undergoing OCNT. (B) Changes in the patient's toenails before and after undergoing OCNT.
CellMed 2023; 13: 3.1-3.4https://doi.org/10.5667/CellMed.spc.035

References

  1. Al Hasan, M., Fitzgerald, S. M., Saoudian, M. & Krishnaswamy, G. Dermatology for the practicing allergist: Tinea pedis and its complications. Clinical and Molecular Allergy 2, 1-11 (2004).
    Pubmed KoreaMed CrossRef
  2. Crawford, F. Athlete's foot. BMJ Clin Evid 2009 (2009).
  3. Markova, T. & Johnson, E. D. What is the most effective treatment for tinea pedis (athlete's foot)? (2002).
  4. Yu, W., Zhu, S.-G., Lu, S.-J., Cai, Z.-X. & Zang, L.-Q. Effect of dimethyl sulfone on anti-inflammatory and immune function in mice. Journal of Hainan Medical University 24, 899-901 (2018).
  5. Tao, S. et al. In vitro antifungal activity and mode of action of selected polyphenolic antioxidants on Botrytis cinerea. Archives of Phytopathology and Plant Protection 43, 1564-1578 (2010).
    CrossRef
  6. Goo, Y.-M. et al. Analysis of antibacterial, anti-inflammatory, and skin-whitening effect of Centella asiatica (L.) Urban. Journal of Plant Biotechnology 45, 117-124 (2018).
    CrossRef
  7. Bulbula, D. D. Comprehensive Review on Turmeric (Curcuma longa l.) as medicinal plant and its nutraceutical quality to human. Cancer therapy and Oncology International Journal 18, 1-3 (2021).
  8. Niamsa, N. & Sittiwet, C. Antimicrobial activity of Curcuma longa aqueous extract. Journal of Pharmacology and Toxicology 4, 173-177 (2009).
    CrossRef
  9. Mudaliana, S. Antimicrobial activity of Centella asiatica and Gigantochloa apus. Journal of Basic and Clinical Physiology and Pharmacology 32, 755-759 (2021).
    Pubmed CrossRef
  10. Jegasothy, S. M., Zabolotniaia, V. & Bielfeldt, S. Efficacy of a new topical nano-hyaluronic acid in humans. The Journal of clinical and aesthetic dermatology 7, 27 (2014).
  11. Danby, S. G. et al. Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care. Pediatric dermatology 30, 42-50 (2013).
    Pubmed CrossRef
  12. Kaźmierska, A. et al. Effect of Evening Primrose Oil Supplementation on Selected Parameters of Skin Condition in a Group of Patients Treated with Isotretinoin—A Randomized Double-Blind Trial. Nutrients 14, 2980 (2022).
    Pubmed KoreaMed CrossRef
  13. Timoszuk, M., Bielawska, K. & Skrzydlewska, E. Evening primrose (Oenothera biennis) biological activity dependent on chemical composition. Antioxidants 7, 108 (2018).
    Pubmed KoreaMed CrossRef
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Apr 30, 2024 Vol.14 No.5, pp. 1.1~5.4

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